Total synthesis of (-)-serotobenine.

نویسندگان

  • Yasuaki Koizumi
  • Hideki Kobayashi
  • Toshiyuki Wakimoto
  • Takumi Furuta
  • Tohru Fukuyama
  • Toshiyuki Kan
چکیده

The efficient total synthesis of (-)-serotobenine (1) has been achieved by constructing an optically active dihydrobenzofuran ring via a rhodium carbenoid mediated intramolecular C-H insertion reaction, which was developed by our group. Then the possibility of racemization of 1 was investigated using optically active synthetic 1.

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عنوان ژورنال:
  • Journal of the American Chemical Society

دوره 130 50  شماره 

صفحات  -

تاریخ انتشار 2008